If you’ve ever dreamed of rich Italian comfort food with a golden, cheesy twist, then this Garlic Butter Shrimp Scampi Lasagna will absolutely light up your dinner table. Imagine tender shrimp nestled between layers of silky garlic-butter cream sauce, ribbons of perfectly cooked noodles, and a bubbling crown of mozzarella. Every bite is creamy, garlicky, and just the right balance of bright, briny seafood with comforting cheese—this is the kind of dish you make when you want to impress friends, treat yourself on a special night in, or shake up classic lasagna with bold new flavors.

Garlic Butter Shrimp Scampi Lasagna Recipe - Recipe Image

Ingredients You’ll Need

The beauty of this lasagna is in its straightforward ingredients—each one is essential, bringing either creamy richness, punchy flavor, or those perfect, tender textures we all crave in a great lasagna. Here’s what you’ll gather to make Garlic Butter Shrimp Scampi Lasagna truly shine:

Lasagna noodles: Classic noodles provide the backbone of every layer and soak up all that garlicky, buttery sauce.
Large shrimp, peeled and deveined: A generous pound of juicy shrimp gives the lasagna its signature scampi flavor.
Garlic, minced: Don’t skimp—this is where the entire dish gets its aromatic punch.
Butter: Half for the shrimp, half for the sauce—because nothing says comfort like real, melty butter.
All-purpose flour: Just enough to thicken your luscious sauce.
Milk: It brings your sauce together, making it smooth and creamy without being heavy.
Parmesan cheese, grated: Freshly grated is best for that salty, nutty backbone.
Mozzarella cheese, shredded: Don’t hold back—a bubbly, browned cheesy top is key!
Fresh parsley, chopped: Sprinkling this over the top adds a burst of freshness and color that lifts the whole dish.
Salt and pepper: Essential for seasoning every single layer just right.
Lemon juice: A splash brightens the sauce and complements the shrimp perfectly.

How to Make Garlic Butter Shrimp Scampi Lasagna

Step 1: Cook the Noodles

Start by boiling your lasagna noodles according to the package instructions. Cook them until they’re perfectly al dente—they’ll soften up further as they bake. Drain them well and set aside. You want these noodles ready and waiting as your base layers for the Garlic Butter Shrimp Scampi Lasagna.

Step 2: Sauté the Garlic and Shrimp

Melt half a cup of butter in a large skillet over medium heat, then add the minced garlic, letting it sizzle until wonderfully fragrant. Toss in the shrimp, season with salt and pepper, and let them turn pink and opaque—about 2-3 minutes per side. As soon as they’re just cooked, scoop them out and set aside; don’t overcook, since they’ll continue to bake later!

Step 3: Make the Garlic Butter Sauce

In the same trusty skillet, melt another half cup of butter and add more minced garlic. Once you’re hit with that glorious aroma, sprinkle in the all-purpose flour and stir for a minute so the flour loses its raw taste. Gradually whisk in the milk—no lumps allowed! Simmer, stirring constantly, until the sauce thickens and coats the back of your spoon.

Step 4: Cheese It Up

Remove the skillet from heat and add grated Parmesan cheese. Let it melt into the sauce, making everything extra creamy and flavorful. Don’t forget to adjust with salt and pepper. Add the fresh parsley and a squeeze of lemon juice for that signature scampi zing.

Step 5: Assemble the Garlic Butter Shrimp Scampi Lasagna

Preheat your oven to 375°F (190°C). In your baking dish, begin with a thin slather of the garlic butter sauce as your base. Lay down noodles, more sauce, a layer of juicy shrimp, and a shower of shredded mozzarella. Continue layering—noodles, sauce, shrimp, cheese—until you’ve used everything, finishing with a final blanket of sauce and a generous topping of mozzarella.

Step 6: Bake Until Golden

Tightly cover your baking dish with foil and bake for 25 minutes. Then, remove the foil and let the lasagna bake an extra 10 minutes to achieve that gorgeous, cheesy, bubbling top. When it comes out of the oven, let it rest for a few moments (if you can wait!) so the layers set a little.

Step 7: Finishing Touches

Right before serving, sprinkle freshly chopped parsley over the top to lift the dish visually and flavor-wise. Now your Garlic Butter Shrimp Scampi Lasagna is ready for the spotlight!

How to Serve Garlic Butter Shrimp Scampi Lasagna

Garnishes

A final flourish of fresh parsley is a must—it adds brightness and a vibrant splash of green. If you’d like to get fancy, add a dusting of extra parmesan and a squeeze of fresh lemon over the lasagna just before serving to dial up that fresh, zesty bite that brings the whole dish together.

Side Dishes

Because Garlic Butter Shrimp Scampi Lasagna is so rich and flavorful, it pairs beautifully with simple sides. Think a peppery arugula salad drizzled with lemon vinaigrette, or a crisp Caesar salad for crunch. A basket of warm, crusty Italian bread is perfect for swiping up every last bit of sauce.

Creative Ways to Present

For a show-stopping dinner party presentation, slice the lasagna neatly and serve each portion atop a nest of garlicky sautéed spinach. Or, bake in individual ramekins for a personalized touch—all the flavor, with built-in portion control and plenty of wow factor.

Make Ahead and Storage

Storing Leftovers

If you’re lucky enough to have leftovers, let the lasagna cool to room temperature before covering tightly with foil or transferring to an airtight container. Store in the fridge for up to 3 days—the flavors actually deepen and meld beautifully overnight!

Freezing

Garlic Butter Shrimp Scampi Lasagna holds up well in the freezer. Assemble it fully, skip the final bake, and wrap securely in foil and plastic wrap. Freeze for up to 2 months. To bake from frozen, simply add 15-20 minutes to the baking time and check to ensure it’s heated through and bubbly.

Reheating

To reheat, cover the lasagna loosely with foil and warm in a 350°F (175°C) oven for 20-25 minutes, or until hot throughout. If the top seems a little dry, drizzle a bit of milk along the edges before reheating to keep it creamy and luscious.

FAQs

Can I use pre-cooked shrimp instead of raw?

Using pre-cooked shrimp is fine, but be sure to add them just before assembling the lasagna so they don’t become tough or rubbery from extra cooking time in the oven.

Is it okay to substitute frozen shrimp?

Absolutely! Just make sure to thaw and pat the shrimp dry before cooking, so your sauce isn’t watery. Frozen shrimp are a handy, budget-friendly choice that works great here.

Can I make Garlic Butter Shrimp Scampi Lasagna ahead of time?

Yes, you can fully assemble the lasagna a day in advance, store it in the fridge, and bake it when you’re ready. This actually lets the flavors mingle and results in an even tastier dish!

How do I prevent my lasagna from being watery?

Make sure to drain the noodles very well, pat dry any cooked shrimp, and let your sauce thicken fully before layering. A thicker sauce is key to a sliceable lasagna that holds together on the plate.

What’s the best way to reheat individual portions?

Microwaving works, but for best texture, reheat slices in a 350°F oven or toaster oven. Place a little foil over the top to keep things moist, then remove the cover for the last few minutes so the cheese gets bubbly again.

Final Thoughts

If you’re craving something a little indulgent, a lot impressive, and truly soul-satisfying, give this Garlic Butter Shrimp Scampi Lasagna a well-deserved spot on your dinner table. It’s a dish that brings people together and turns any night into a special occasion—so go ahead, gather your ingredients and dive in!