Cowboy Biscuit Casserole Recipe
Introduction
This Cowboy Biscuit Casserole is a hearty and comforting dish perfect for family dinners. Featuring layers of cheesy biscuits, seasoned ground beef, and a creamy topping, it’s a satisfying meal that’s easy to put together and sure to please everyone at the table.

Ingredients
- 1 Box Red Lobster Cheddar Bay Biscuit Mix (plus the water on the package instructions and flavoring packet)
- 1 Tbsp Olive Oil
- ½ Onion, chopped
- 3 Cloves Garlic, chopped
- 1–1.5 Pounds Ground Beef
- 2 Oz Taco Seasoning
- 1 Cup Sour Cream
- ½ Cup Mayonnaise
- 2 Cups Cheddar Cheese, hand shredded (divided)
- Salt and Pepper to taste
- 1 Tbsp Garlic Powder
Instructions
- Step 1: Preheat your oven to 350°F (175°C).
- Step 2: In a large bowl, combine the biscuit mix with the water according to the package instructions. Add the seasoning packet included in the mix for extra flavor, then press this sticky dough evenly into the bottom of a greased 9 x 13-inch baking dish using your fingers.
- Step 3: Heat olive oil in a large skillet over medium heat. Sauté the chopped onion and garlic until they are soft and fragrant.
- Step 4: Add the ground beef to the skillet and cook thoroughly, stirring and breaking it up as it browns. Mix in the taco seasoning and stir well, then spread the seasoned beef evenly over the biscuit layer in the baking dish.
- Step 5: In a medium bowl, combine sour cream, mayonnaise, half of the shredded cheddar cheese, salt, pepper, and garlic powder. Stir until the mixture is smooth, then pour it over the beef layer and spread evenly.
- Step 6: Sprinkle the remaining cheddar cheese on top, then place the casserole in the center rack of the preheated oven. Bake for 30 to 35 minutes, until the cheese is melted and bubbly and the biscuits are cooked through.
- Step 7: Remove the casserole from the oven and let it rest for 5 to 10 minutes. Sprinkle with dried parsley if desired, then serve and enjoy.
Tips & Variations
- Use fresh garlic and onion for the best flavor, but garlic powder and onion powder can substitute in a pinch.
- Try adding diced bell peppers or jalapeños to the beef for extra color and spice.
- If you prefer, switch ground beef for ground turkey or chicken for a lighter option.
- Top with sliced green onions or a dollop of salsa for added freshness.
Storage
Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat individual portions in the microwave or the entire casserole in a 350°F oven until warmed through. This dish can also be frozen for up to 2 months; thaw overnight in the refrigerator before reheating.
How to Serve

Serve this delicious recipe with your favorite sides.
FAQs
Can I make this casserole ahead of time?
Yes, you can assemble the casserole a few hours ahead and keep it covered in the refrigerator. Bake just before serving for the best texture and flavor.
Can I use a different biscuit mix?
Yes, you can substitute any biscuit mix, but using a cheddar-flavored one enhances the cheesy richness that complements the beef and creamy layers well.
PrintCowboy Biscuit Casserole Recipe
This Cowboy Biscuit Casserole is a hearty and flavorful layered dish combining savory ground beef seasoned with taco spices, a creamy cheese and sour cream topping, and a golden cheddar biscuit base using Red Lobster Cheddar Bay Biscuit Mix. Perfect for a comforting family dinner, it bakes to bubbly, cheesy perfection with a crispy biscuit crust.
- Prep Time: 15 minutes
- Cook Time: 35 minutes
- Total Time: 50 minutes
- Yield: 6 to 8 servings 1x
- Category: Casserole
- Method: Baking
- Cuisine: American
Ingredients
Biscuit Base
- 1 Box Red Lobster Cheddar Bay Biscuit Mix (includes seasoning packet and water as per package instructions)
Beef Mixture
- 1 Tablespoon Olive Oil
- ½ Onion, chopped
- 3 Cloves Garlic, chopped
- 1 to 1.5 Pounds Ground Beef
- 2 Ounces Taco Seasoning (approximately two packets)
Creamy Cheese Topping
- 1 Cup Sour Cream
- ½ Cup Mayonnaise
- 1 Cup Cheddar Cheese, hand shredded (half of 2 cups)
- Salt and Pepper, to taste
- 1 Tablespoon Garlic Powder
- 1 Cup Cheddar Cheese, hand shredded (remaining half for topping)
Garnish
- Dried parsley, for sprinkling on top (optional)
Instructions
- Preheat Oven: Set your oven to 350°F (175°C) to prepare for baking the casserole.
- Prepare Biscuit Base: In a large bowl, combine the Red Lobster Cheddar Bay Biscuit Mix with the required amount of water as indicated on the package. Stir well to form a sticky dough. Mix in the seasoning packet from the biscuit mix for added flavor. Press this dough evenly into the bottom of a greased 9 x 13-inch baking dish using your fingers, ensuring it’s distributed to form a solid base.
- Sauté Aromatics: Heat olive oil in a large skillet over medium heat. Add the chopped onion and garlic and sauté until softened and fragrant, about 3-5 minutes.
- Cook Ground Beef: Add the ground beef to the skillet with the sautéed aromatics. Sprinkle the taco seasoning evenly over the meat and cook, stirring occasionally, until the beef is thoroughly browned and cooked through, breaking it up into small pieces as it cooks. This typically takes 7-10 minutes. Drain any excess grease if necessary.
- Layer Beef over Biscuit Base: Spread the seasoned cooked beef mixture evenly over the pressed biscuit dough in the baking dish.
- Prepare Creamy Topping: In a medium bowl, combine the sour cream, mayonnaise, half of the shredded cheddar cheese (1 cup), garlic powder, salt, and pepper. Mix until fully incorporated and smooth.
- Spread Topping: Pour the creamy cheese mixture evenly over the ground beef layer, smoothing it out with a spatula for an even top layer.
- Add Remaining Cheese: Sprinkle the remaining 1 cup of shredded cheddar cheese generously over the creamy topping layer.
- Bake Casserole: Place the casserole dish on the center rack of your preheated oven. Bake uncovered for 30 to 35 minutes, or until the biscuit base is cooked through and golden brown, and the cheese is melted and bubbly.
- Rest and Serve: Remove the casserole from the oven and let it rest for 5 to 10 minutes to set. Optionally, sprinkle dried parsley on top before serving for a touch of color and flavor. Serve warm and enjoy!
Notes
- You can adjust the amount of taco seasoning based on your spice preference; two packets add robust flavor.
- Using the seasoning packet from the biscuit mix enhances the biscuit base’s flavor, but you can omit it for a milder taste.
- Ensure the biscuit dough is pressed firmly and evenly for a solid crust layer.
- Letting the casserole rest after baking helps it to firm up, making serving easier.
- Feel free to substitute ground turkey or chicken for a leaner option.
Keywords: Cowboy Biscuit Casserole, Cheddar Bay Biscuits, Ground Beef Casserole, Cheesy Beef Bake, Red Lobster Biscuit Casserole

